WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:system process       ID:GO:0003008
C=1695; O=16; E=4.87; R=3.29; rawP=8.54e-06; adjP=0.0043
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
3  ENSG00000204248 NA COL11A2 collagen, type XI, alpha 2 1302 ENSG00000204248
4  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
5  ENSG00000125878 NA TCF15 transcription factor 15 (basic helix-loop-helix) 6939 ENSG00000125878
6  ENSG00000107736 NA CDH23 cadherin-related 23 64072 ENSG00000107736
7  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
8  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
9  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
10  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
11  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
12  ENSG00000169894 NA MUC3A mucin 3A, cell surface associated 4584 ENSG00000169894
13  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
14  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
15  ENSG00000074416 NA MGLL monoglyceride lipase 11343 ENSG00000074416
16  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204


Database:biological process       Name:multicellular organismal process       ID:GO:0032501
C=5644; O=29; E=16.20; R=1.79; rawP=6.04e-05; adjP=0.0084
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000143772 NA ITPKB inositol-trisphosphate 3-kinase B 3707 ENSG00000143772
3  ENSG00000054179 NA ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 954 ENSG00000054179
4  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
5  ENSG00000129757 NA CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1028 ENSG00000129757
6  ENSG00000204248 NA COL11A2 collagen, type XI, alpha 2 1302 ENSG00000204248
7  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
8  ENSG00000125878 NA TCF15 transcription factor 15 (basic helix-loop-helix) 6939 ENSG00000125878
9  ENSG00000107736 NA CDH23 cadherin-related 23 64072 ENSG00000107736
10  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434
11  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
12  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
13  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
14  ENSG00000134986 NA NREP neuronal regeneration related protein homolog (rat) 9315 ENSG00000134986
15  ENSG00000135439 NA AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 116986 ENSG00000135439
16  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
17  ENSG00000066735 NA KIF26A kinesin family member 26A 26153 ENSG00000066735
18  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421
19  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
20  ENSG00000135299 NA ANKRD6 ankyrin repeat domain 6 22881 ENSG00000135299
21  ENSG00000169894 NA MUC3A mucin 3A, cell surface associated 4584 ENSG00000169894
22  ENSG00000129993 NA CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 863 ENSG00000129993
23  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
24  ENSG00000167178 NA ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 57611 ENSG00000167178
25  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
26  ENSG00000040608 NA RTN4R reticulon 4 receptor 65078 ENSG00000040608
27  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204
28  ENSG00000074416 NA MGLL monoglyceride lipase 11343 ENSG00000074416
29  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721


Database:biological process       Name:regulation of multicellular organismal process       ID:GO:0051239
C=1772; O=15; E=5.09; R=2.95; rawP=6.72e-05; adjP=0.0084
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143772 NA ITPKB inositol-trisphosphate 3-kinase B 3707 ENSG00000143772
2  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
3  ENSG00000135299 NA ANKRD6 ankyrin repeat domain 6 22881 ENSG00000135299
4  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
5  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
6  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
7  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
8  ENSG00000134986 NA NREP neuronal regeneration related protein homolog (rat) 9315 ENSG00000134986
9  ENSG00000167178 NA ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 57611 ENSG00000167178
10  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
11  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
12  ENSG00000040608 NA RTN4R reticulon 4 receptor 65078 ENSG00000040608
13  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204
14  ENSG00000074416 NA MGLL monoglyceride lipase 11343 ENSG00000074416
15  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421


Database:biological process       Name:regulation of biological quality       ID:GO:0065008
C=2511; O=18; E=7.21; R=2.50; rawP=8.41e-05; adjP=0.0084
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000054179 NA ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 954 ENSG00000054179
2  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
3  ENSG00000204248 NA COL11A2 collagen, type XI, alpha 2 1302 ENSG00000204248
4  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
5  ENSG00000107736 NA CDH23 cadherin-related 23 64072 ENSG00000107736
6  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
7  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
8  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
9  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
10  ENSG00000167996 NA FTH1 ferritin, heavy polypeptide 1 2495 ENSG00000167996
11  ENSG00000066735 NA KIF26A kinesin family member 26A 26153 ENSG00000066735
12  ENSG00000169894 NA MUC3A mucin 3A, cell surface associated 4584 ENSG00000169894
13  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
14  ENSG00000167178 NA ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 57611 ENSG00000167178
15  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
16  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204
17  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721
18  ENSG00000074416 NA MGLL monoglyceride lipase 11343 ENSG00000074416


Database:biological process       Name:single-organism process       ID:GO:0044699
C=7682; O=34; E=22.05; R=1.54; rawP=0.0001; adjP=0.0084
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000143772 NA ITPKB inositol-trisphosphate 3-kinase B 3707 ENSG00000143772
3  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
4  ENSG00000129757 NA CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1028 ENSG00000129757
5  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
6  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434
7  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
8  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
9  ENSG00000134986 NA NREP neuronal regeneration related protein homolog (rat) 9315 ENSG00000134986
10  ENSG00000215788 NA TNFRSF25 tumor necrosis factor receptor superfamily, member 25 8718 ENSG00000215788
11  ENSG00000066735 NA KIF26A kinesin family member 26A 26153 ENSG00000066735
12  ENSG00000100065 NA CARD10 caspase recruitment domain family, member 10 29775 ENSG00000100065
13  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421
14  ENSG00000171680 NA PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 57449 ENSG00000171680
15  ENSG00000129993 NA CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 863 ENSG00000129993
16  ENSG00000169894 NA MUC3A mucin 3A, cell surface associated 4584 ENSG00000169894
17  ENSG00000109917 NA ZNF259 zinc finger protein 259 8882 ENSG00000109917
18  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
19  ENSG00000167178 NA ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 57611 ENSG00000167178
20  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
21  ENSG00000074416 NA MGLL monoglyceride lipase 11343 ENSG00000074416
22  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721
23  ENSG00000168067 NA MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 5871 ENSG00000168067
24  ENSG00000054179 NA ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 954 ENSG00000054179
25  ENSG00000204248 NA COL11A2 collagen, type XI, alpha 2 1302 ENSG00000204248
26  ENSG00000107736 NA CDH23 cadherin-related 23 64072 ENSG00000107736
27  ENSG00000125878 NA TCF15 transcription factor 15 (basic helix-loop-helix) 6939 ENSG00000125878
28  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
29  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
30  ENSG00000135439 NA AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 116986 ENSG00000135439
31  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
32  ENSG00000135299 NA ANKRD6 ankyrin repeat domain 6 22881 ENSG00000135299
33  ENSG00000040608 NA RTN4R reticulon 4 receptor 65078 ENSG00000040608
34  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204


Database:biological process       Name:single-multicellular organism process       ID:GO:0044707
C=5612; O=29; E=16.11; R=1.80; rawP=5.35e-05; adjP=0.0084
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000143772 NA ITPKB inositol-trisphosphate 3-kinase B 3707 ENSG00000143772
3  ENSG00000054179 NA ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 954 ENSG00000054179
4  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
5  ENSG00000129757 NA CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1028 ENSG00000129757
6  ENSG00000204248 NA COL11A2 collagen, type XI, alpha 2 1302 ENSG00000204248
7  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
8  ENSG00000125878 NA TCF15 transcription factor 15 (basic helix-loop-helix) 6939 ENSG00000125878
9  ENSG00000107736 NA CDH23 cadherin-related 23 64072 ENSG00000107736
10  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434
11  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
12  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
13  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
14  ENSG00000134986 NA NREP neuronal regeneration related protein homolog (rat) 9315 ENSG00000134986
15  ENSG00000135439 NA AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 116986 ENSG00000135439
16  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
17  ENSG00000066735 NA KIF26A kinesin family member 26A 26153 ENSG00000066735
18  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421
19  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
20  ENSG00000135299 NA ANKRD6 ankyrin repeat domain 6 22881 ENSG00000135299
21  ENSG00000169894 NA MUC3A mucin 3A, cell surface associated 4584 ENSG00000169894
22  ENSG00000129993 NA CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 863 ENSG00000129993
23  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
24  ENSG00000167178 NA ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 57611 ENSG00000167178
25  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
26  ENSG00000040608 NA RTN4R reticulon 4 receptor 65078 ENSG00000040608
27  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204
28  ENSG00000074416 NA MGLL monoglyceride lipase 11343 ENSG00000074416
29  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721


Database:biological process       Name:biological regulation       ID:GO:0065007
C=8617; O=36; E=24.74; R=1.46; rawP=0.0002; adjP=0.0145
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000143772 NA ITPKB inositol-trisphosphate 3-kinase B 3707 ENSG00000143772
3  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
4  ENSG00000129757 NA CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1028 ENSG00000129757
5  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
6  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
7  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
8  ENSG00000134986 NA NREP neuronal regeneration related protein homolog (rat) 9315 ENSG00000134986
9  ENSG00000167996 NA FTH1 ferritin, heavy polypeptide 1 2495 ENSG00000167996
10  ENSG00000215788 NA TNFRSF25 tumor necrosis factor receptor superfamily, member 25 8718 ENSG00000215788
11  ENSG00000066735 NA KIF26A kinesin family member 26A 26153 ENSG00000066735
12  ENSG00000100065 NA CARD10 caspase recruitment domain family, member 10 29775 ENSG00000100065
13  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421
14  ENSG00000171680 NA PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 57449 ENSG00000171680
15  ENSG00000129993 NA CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 863 ENSG00000129993
16  ENSG00000169894 NA MUC3A mucin 3A, cell surface associated 4584 ENSG00000169894
17  ENSG00000109917 NA ZNF259 zinc finger protein 259 8882 ENSG00000109917
18  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
19  ENSG00000167178 NA ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 57611 ENSG00000167178
20  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
21  ENSG00000074416 NA MGLL monoglyceride lipase 11343 ENSG00000074416
22  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721
23  ENSG00000164105 NA SAP30 Sin3A-associated protein, 30kDa 8819 ENSG00000164105
24  ENSG00000168067 NA MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 5871 ENSG00000168067
25  ENSG00000054179 NA ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 954 ENSG00000054179
26  ENSG00000204248 NA COL11A2 collagen, type XI, alpha 2 1302 ENSG00000204248
27  ENSG00000107736 NA CDH23 cadherin-related 23 64072 ENSG00000107736
28  ENSG00000125878 NA TCF15 transcription factor 15 (basic helix-loop-helix) 6939 ENSG00000125878
29  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
30  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
31  ENSG00000135439 NA AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 116986 ENSG00000135439
32  ENSG00000198169 NA ZNF251 zinc finger protein 251 90987 ENSG00000198169
33  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
34  ENSG00000135299 NA ANKRD6 ankyrin repeat domain 6 22881 ENSG00000135299
35  ENSG00000040608 NA RTN4R reticulon 4 receptor 65078 ENSG00000040608
36  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204


Database:biological process       Name:digestion       ID:GO:0007586
C=114; O=4; E=0.33; R=12.22; rawP=0.0003; adjP=0.0190
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000169894 NA MUC3A mucin 3A, cell surface associated 4584 ENSG00000169894
3  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
4  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583


Database:biological process       Name:renal system process       ID:GO:0003014
C=70; O=3; E=0.20; R=14.93; rawP=0.0011; adjP=0.0293
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
2  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204
3  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583


Database:biological process       Name:multicellular organismal water homeostasis       ID:GO:0050891
C=17; O=2; E=0.05; R=40.98; rawP=0.0011; adjP=0.0293
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204
2  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583


Database:molecular function       Name:passive transmembrane transporter activity       ID:GO:0022803
C=420; O=5; E=1.24; R=4.04; rawP=0.0076; adjP=0.0567
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
2  ENSG00000094755 NA GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2568 ENSG00000094755
3  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
4  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
5  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583


Database:molecular function       Name:ion gated channel activity       ID:GO:0022839
C=303; O=5; E=0.89; R=5.60; rawP=0.0019; adjP=0.0567
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
2  ENSG00000094755 NA GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2568 ENSG00000094755
3  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
4  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
5  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583


Database:molecular function       Name:potassium channel regulator activity       ID:GO:0015459
C=29; O=2; E=0.09; R=23.42; rawP=0.0033; adjP=0.0567
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
2  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132


Database:molecular function       Name:channel activity       ID:GO:0015267
C=420; O=5; E=1.24; R=4.04; rawP=0.0076; adjP=0.0567
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
2  ENSG00000094755 NA GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2568 ENSG00000094755
3  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
4  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
5  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583


Database:molecular function       Name:potassium channel activity       ID:GO:0005267
C=110; O=3; E=0.32; R=9.26; rawP=0.0041; adjP=0.0567
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
2  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
3  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583


Database:molecular function       Name:Ras guanyl-nucleotide exchange factor activity       ID:GO:0005088
C=112; O=3; E=0.33; R=9.10; rawP=0.0043; adjP=0.0567
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000146966 NA DENND2A DENN/MADD domain containing 2A 27147 ENSG00000146966
2  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
3  ENSG00000171680 NA PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 57449 ENSG00000171680


Database:molecular function       Name:potassium ion transmembrane transporter activity       ID:GO:0015079
C=125; O=3; E=0.37; R=8.15; rawP=0.0059; adjP=0.0567
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
2  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
3  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583


Database:molecular function       Name:ion transmembrane transporter activity       ID:GO:0015075
C=786; O=7; E=2.31; R=3.02; rawP=0.0076; adjP=0.0567
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
2  ENSG00000135502 NA SLC26A10 solute carrier family 26, member 10 65012 ENSG00000135502
3  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
4  ENSG00000094755 NA GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2568 ENSG00000094755
5  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
6  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
7  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583


Database:molecular function       Name:ion channel activity       ID:GO:0005216
C=393; O=5; E=1.16; R=4.32; rawP=0.0058; adjP=0.0567
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
2  ENSG00000094755 NA GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2568 ENSG00000094755
3  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
4  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
5  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583


Database:molecular function       Name:small GTPase regulator activity       ID:GO:0005083
C=299; O=5; E=0.88; R=5.68; rawP=0.0018; adjP=0.0567
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000146966 NA DENND2A DENN/MADD domain containing 2A 27147 ENSG00000146966
2  ENSG00000135439 NA AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 116986 ENSG00000135439
3  ENSG00000168067 NA MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 5871 ENSG00000168067
4  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
5  ENSG00000171680 NA PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 57449 ENSG00000171680


Database:cellular component       Name:plasma membrane part       ID:GO:0044459
C=1918; O=15; E=5.74; R=2.62; rawP=0.0003; adjP=0.0197
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000168067 NA MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 5871 ENSG00000168067
3  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
4  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
5  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
6  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
7  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434
8  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
9  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
10  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
11  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
12  ENSG00000215788 NA TNFRSF25 tumor necrosis factor receptor superfamily, member 25 8718 ENSG00000215788
13  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204
14  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721
15  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421


Database:cellular component       Name:membrane part       ID:GO:0044425
C=6154; O=30; E=18.40; R=1.63; rawP=0.0008; adjP=0.0197
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170537 NA TMC7 transmembrane channel-like 7 79905 ENSG00000170537
2  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
3  ENSG00000168067 NA MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 5871 ENSG00000168067
4  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
5  ENSG00000054179 NA ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 954 ENSG00000054179
6  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
7  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
8  ENSG00000107736 NA CDH23 cadherin-related 23 64072 ENSG00000107736
9  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434
10  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
11  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
12  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
13  ENSG00000078596 NA ITM2A integral membrane protein 2A 9452 ENSG00000078596
14  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
15  ENSG00000215788 NA TNFRSF25 tumor necrosis factor receptor superfamily, member 25 8718 ENSG00000215788
16  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421
17  ENSG00000135502 NA SLC26A10 solute carrier family 26, member 10 65012 ENSG00000135502
18  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
19  ENSG00000180785 NA OR51E1 olfactory receptor, family 51, subfamily E, member 1 143503 ENSG00000180785
20  ENSG00000132563 NA REEP2 receptor accessory protein 2 51308 ENSG00000132563
21  ENSG00000169894 NA MUC3A mucin 3A, cell surface associated 4584 ENSG00000169894
22  ENSG00000094755 NA GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2568 ENSG00000094755
23  ENSG00000167178 NA ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 57611 ENSG00000167178
24  ENSG00000166265 NA CYYR1 cysteine/tyrosine-rich 1 116159 ENSG00000166265
25  ENSG00000040608 NA RTN4R reticulon 4 receptor 65078 ENSG00000040608
26  ENSG00000130032 NA PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 79057 ENSG00000130032
27  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204
28  ENSG00000074416 NA MGLL monoglyceride lipase 11343 ENSG00000074416
29  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721
30  ENSG00000136114 NA THSD1 thrombospondin, type I, domain containing 1 55901 ENSG00000136114


Database:cellular component       Name:intrinsic to membrane       ID:GO:0031224
C=5437; O=28; E=16.26; R=1.72; rawP=0.0006; adjP=0.0197
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170537 NA TMC7 transmembrane channel-like 7 79905 ENSG00000170537
2  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
3  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
4  ENSG00000054179 NA ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 954 ENSG00000054179
5  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
6  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
7  ENSG00000107736 NA CDH23 cadherin-related 23 64072 ENSG00000107736
8  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434
9  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
10  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
11  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
12  ENSG00000078596 NA ITM2A integral membrane protein 2A 9452 ENSG00000078596
13  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
14  ENSG00000215788 NA TNFRSF25 tumor necrosis factor receptor superfamily, member 25 8718 ENSG00000215788
15  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421
16  ENSG00000135502 NA SLC26A10 solute carrier family 26, member 10 65012 ENSG00000135502
17  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
18  ENSG00000180785 NA OR51E1 olfactory receptor, family 51, subfamily E, member 1 143503 ENSG00000180785
19  ENSG00000132563 NA REEP2 receptor accessory protein 2 51308 ENSG00000132563
20  ENSG00000169894 NA MUC3A mucin 3A, cell surface associated 4584 ENSG00000169894
21  ENSG00000094755 NA GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2568 ENSG00000094755
22  ENSG00000167178 NA ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 57611 ENSG00000167178
23  ENSG00000166265 NA CYYR1 cysteine/tyrosine-rich 1 116159 ENSG00000166265
24  ENSG00000040608 NA RTN4R reticulon 4 receptor 65078 ENSG00000040608
25  ENSG00000130032 NA PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 79057 ENSG00000130032
26  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204
27  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721
28  ENSG00000136114 NA THSD1 thrombospondin, type I, domain containing 1 55901 ENSG00000136114


Database:cellular component       Name:intrinsic to plasma membrane       ID:GO:0031226
C=1264; O=11; E=3.78; R=2.91; rawP=0.0011; adjP=0.0204
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
3  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
4  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
5  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434
6  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
7  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
8  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
9  ENSG00000215788 NA TNFRSF25 tumor necrosis factor receptor superfamily, member 25 8718 ENSG00000215788
10  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721
11  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421


Database:cellular component       Name:plasma membrane       ID:GO:0005886
C=4289; O=23; E=12.83; R=1.79; rawP=0.0015; adjP=0.0222
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000168067 NA MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 5871 ENSG00000168067
3  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
4  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
5  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
6  ENSG00000107736 NA CDH23 cadherin-related 23 64072 ENSG00000107736
7  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434
8  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
9  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
10  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
11  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
12  ENSG00000215788 NA TNFRSF25 tumor necrosis factor receptor superfamily, member 25 8718 ENSG00000215788
13  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421
14  ENSG00000171680 NA PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 57449 ENSG00000171680
15  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
16  ENSG00000180785 NA OR51E1 olfactory receptor, family 51, subfamily E, member 1 143503 ENSG00000180785
17  ENSG00000094755 NA GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2568 ENSG00000094755
18  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
19  ENSG00000167178 NA ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 57611 ENSG00000167178
20  ENSG00000040608 NA RTN4R reticulon 4 receptor 65078 ENSG00000040608
21  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204
22  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721
23  ENSG00000074416 NA MGLL monoglyceride lipase 11343 ENSG00000074416


Database:cellular component       Name:cell periphery       ID:GO:0071944
C=4377; O=23; E=13.09; R=1.76; rawP=0.0020; adjP=0.0247
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000168067 NA MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 5871 ENSG00000168067
3  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
4  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
5  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
6  ENSG00000107736 NA CDH23 cadherin-related 23 64072 ENSG00000107736
7  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434
8  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
9  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
10  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
11  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
12  ENSG00000215788 NA TNFRSF25 tumor necrosis factor receptor superfamily, member 25 8718 ENSG00000215788
13  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421
14  ENSG00000171680 NA PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 57449 ENSG00000171680
15  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
16  ENSG00000180785 NA OR51E1 olfactory receptor, family 51, subfamily E, member 1 143503 ENSG00000180785
17  ENSG00000094755 NA GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2568 ENSG00000094755
18  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
19  ENSG00000167178 NA ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 57611 ENSG00000167178
20  ENSG00000040608 NA RTN4R reticulon 4 receptor 65078 ENSG00000040608
21  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204
22  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721
23  ENSG00000074416 NA MGLL monoglyceride lipase 11343 ENSG00000074416


Database:cellular component       Name:integral to membrane       ID:GO:0016021
C=5321; O=26; E=15.91; R=1.63; rawP=0.0025; adjP=0.0264
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170537 NA TMC7 transmembrane channel-like 7 79905 ENSG00000170537
2  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
3  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
4  ENSG00000054179 NA ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 954 ENSG00000054179
5  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
6  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
7  ENSG00000107736 NA CDH23 cadherin-related 23 64072 ENSG00000107736
8  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
9  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
10  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
11  ENSG00000078596 NA ITM2A integral membrane protein 2A 9452 ENSG00000078596
12  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
13  ENSG00000215788 NA TNFRSF25 tumor necrosis factor receptor superfamily, member 25 8718 ENSG00000215788
14  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421
15  ENSG00000135502 NA SLC26A10 solute carrier family 26, member 10 65012 ENSG00000135502
16  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
17  ENSG00000180785 NA OR51E1 olfactory receptor, family 51, subfamily E, member 1 143503 ENSG00000180785
18  ENSG00000132563 NA REEP2 receptor accessory protein 2 51308 ENSG00000132563
19  ENSG00000169894 NA MUC3A mucin 3A, cell surface associated 4584 ENSG00000169894
20  ENSG00000094755 NA GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2568 ENSG00000094755
21  ENSG00000167178 NA ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 57611 ENSG00000167178
22  ENSG00000166265 NA CYYR1 cysteine/tyrosine-rich 1 116159 ENSG00000166265
23  ENSG00000130032 NA PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 79057 ENSG00000130032
24  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204
25  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721
26  ENSG00000136114 NA THSD1 thrombospondin, type I, domain containing 1 55901 ENSG00000136114


Database:cellular component       Name:integral to plasma membrane       ID:GO:0005887
C=1220; O=10; E=3.65; R=2.74; rawP=0.0029; adjP=0.0268
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
3  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
4  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
5  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
6  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
7  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
8  ENSG00000215788 NA TNFRSF25 tumor necrosis factor receptor superfamily, member 25 8718 ENSG00000215788
9  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721
10  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421


Database:cellular component       Name:membrane       ID:GO:0016020
C=7811; O=33; E=23.36; R=1.41; rawP=0.0050; adjP=0.0411
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000126895 NA AVPR2 arginine vasopressin receptor 2 554 ENSG00000126895
3  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
4  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434
5  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
6  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
7  ENSG00000215788 NA TNFRSF25 tumor necrosis factor receptor superfamily, member 25 8718 ENSG00000215788
8  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421
9  ENSG00000171680 NA PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 57449 ENSG00000171680
10  ENSG00000135502 NA SLC26A10 solute carrier family 26, member 10 65012 ENSG00000135502
11  ENSG00000180785 NA OR51E1 olfactory receptor, family 51, subfamily E, member 1 143503 ENSG00000180785
12  ENSG00000132563 NA REEP2 receptor accessory protein 2 51308 ENSG00000132563
13  ENSG00000169894 NA MUC3A mucin 3A, cell surface associated 4584 ENSG00000169894
14  ENSG00000129993 NA CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 863 ENSG00000129993
15  ENSG00000094755 NA GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2568 ENSG00000094755
16  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
17  ENSG00000166265 NA CYYR1 cysteine/tyrosine-rich 1 116159 ENSG00000166265
18  ENSG00000167178 NA ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 57611 ENSG00000167178
19  ENSG00000074416 NA MGLL monoglyceride lipase 11343 ENSG00000074416
20  ENSG00000136114 NA THSD1 thrombospondin, type I, domain containing 1 55901 ENSG00000136114
21  ENSG00000154721 NA JAM2 junctional adhesion molecule 2 58494 ENSG00000154721
22  ENSG00000170537 NA TMC7 transmembrane channel-like 7 79905 ENSG00000170537
23  ENSG00000168067 NA MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 5871 ENSG00000168067
24  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
25  ENSG00000054179 NA ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 954 ENSG00000054179
26  ENSG00000107736 NA CDH23 cadherin-related 23 64072 ENSG00000107736
27  ENSG00000078596 NA ITM2A integral membrane protein 2A 9452 ENSG00000078596
28  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
29  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
30  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
31  ENSG00000040608 NA RTN4R reticulon 4 receptor 65078 ENSG00000040608
32  ENSG00000130032 NA PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 79057 ENSG00000130032
33  ENSG00000186204 NA CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 66002 ENSG00000186204


Database:cellular component       Name:brush border membrane       ID:GO:0031526
C=38; O=2; E=0.11; R=17.60; rawP=0.0058; adjP=0.0429
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434
2  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).